Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIG1 All Species: 19.09
Human Site: S468 Identified Species: 38.18
UniProt: P18858 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18858 NP_000225.1 919 101736 S468 A A L S Q A V S L T P P G Q E
Chimpanzee Pan troglodytes XP_524321 919 101662 S468 A A L S Q A V S L T P P G Q E
Rhesus Macaque Macaca mulatta XP_001111346 919 101454 S468 A A L S Q A V S L T P P G Q E
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P37913 916 102271 S466 A A L A Q A V S L T P P G Q E
Rat Rattus norvegicus Q9JHY8 918 102463 S468 A A L A Q A G S L T P P G Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis P51892 1070 120215 C621 S S I A Q A V C L T P P G R D
Zebra Danio Brachydanio rerio NP_001119860 1058 118776 C610 A A L S Q A V C L T P P G Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1H4 747 84700 T327 K D E I V D T T L L L K T A Y
Honey Bee Apis mellifera XP_392286 861 97795 K429 P E I L D V S K K M S N D T F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001180844 967 108403 A519 V A L G H A G A L A K P E S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42572 790 87722 S370 K P P P N T K S P L E E A A K
Baker's Yeast Sacchar. cerevisiae P04819 755 84810 E335 L L H D E N R E D S P D K D V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 98.2 N.A. N.A. 84 81.3 N.A. N.A. N.A. 56.9 56.1 N.A. 44 46 N.A. 48.5
Protein Similarity: 100 99.4 98.8 N.A. N.A. 89.3 87.8 N.A. N.A. N.A. 71.1 68.6 N.A. 60.2 65.7 N.A. 66.2
P-Site Identity: 100 100 100 N.A. N.A. 93.3 86.6 N.A. N.A. N.A. 53.3 93.3 N.A. 6.6 0 N.A. 33.3
P-Site Similarity: 100 100 100 N.A. N.A. 100 93.3 N.A. N.A. N.A. 93.3 93.3 N.A. 13.3 6.6 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 40.3 36 N.A.
Protein Similarity: N.A. N.A. N.A. 58.3 53.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 59 0 25 0 67 0 9 0 9 0 0 9 17 0 % A
% Cys: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 9 9 9 0 0 9 0 0 9 9 9 17 % D
% Glu: 0 9 9 0 9 0 0 9 0 0 9 9 9 0 50 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 0 0 0 9 0 0 17 0 0 0 0 0 59 0 0 % G
% His: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 17 9 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 17 0 0 0 0 0 9 9 9 0 9 9 9 0 9 % K
% Leu: 9 9 59 9 0 0 0 0 75 17 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 9 0 0 0 0 0 9 0 0 0 % N
% Pro: 9 9 9 9 0 0 0 0 9 0 67 67 0 0 0 % P
% Gln: 0 0 0 0 59 0 0 0 0 0 0 0 0 50 0 % Q
% Arg: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % R
% Ser: 9 9 0 34 0 0 9 50 0 9 9 0 0 9 0 % S
% Thr: 0 0 0 0 0 9 9 9 0 59 0 0 9 9 0 % T
% Val: 9 0 0 0 9 9 50 0 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _